Before a crowd of 3361 in the Brandt Centre, Pats phenom Sam Steel put the homeside up 1-0 with a shorthanded goal 12 minutes into the opening period. The lead held up into the second.
The Tigers' Max Gerlach tied the game late in the second period and it was 1-1 after 40 minutes. However Regina broke loose with three in the third frame, from Jake Leschyshyn, Austin Wagner and Adam Brooks (empty net).
Tyler Brown made 35 saves to collect the win in the Regina goal while Medicine Hat's Mack Shields made 25 saves in a losing cause.
The Tigers outshot the Pats 37-29 as Regina went 0/6 on the powerplay and 3/3 killing penalties. The game even featured a pair of spirited fights and the Tigers' Alex Mowbray was assessed a 5-minute major for charging midway through the third period however the Pats failed to capitalize.
Regina (10-8-1) now plays nine straight on the road beginning Friday night in Brandon (7:30 pm on 620 CKRM).